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- Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in men with established coronary artery illness .
- Effects of testosterone on coronary vasomotor regulation in men with coronary heart illness.
- Physicians and patients ought to be aware of the scientific consequences of anabolic steroid abuse.
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Moreover, a part of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity. However, testosterone in physiologic doses could even be helpful in patients with angina , have greater ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood flow in men with established coronary artery disease . Therefore, an interaction of endogenous factors of the patient’s danger profile in addition to the testosterone dosing could also be problems with whether or not adverse events happen.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac risk factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, doubtless secondary to high-dose testosterone. The affected person underwent successful percutaneous intervention of the best coronary artery. Physicians and patients should pay consideration to the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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